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/ / Safety Profile of TRT


Safety Profile of TRT


28 November 2024 | 


Is Testosterone Replacement Therapy Safe?


Broadly speaking, yes, is safe. indicates that testosterone replacement therpay is considered safe in most men, and can also largely beneficial in improving health-related quality of life.


As a clinic with a strict patient-first approach, we will always make sure that the treatment we provide is what is right for you and your long-term health and we use


Why Understanding TRT is Essential to Your Health Journey


is a game changing option for men experiencing the effects of low testosterone (Low T), those aged 40 upwards. With benefits ranging from enhanced energy to improved muscle tone and mood, TRT can make a big difference to the quality of your life. However, as with any medical treatment, understanding both it’s potential benefits and risks is essential for informed decision-making.


At Omniya Clinic London, we’re committed to guiding you through this journey with clear, research-based information. Let’s break down the potential risks, safety considerations, and side effects of TRT, so you can feel confident in your decision-making .


What Are the Risks of Testosterone Replacement Therapy?


is generally considered safe when administered and monitored by professionals, certain risks are associated with the treatment. These risks are often tied to health factors and require careful assessment and management. These risks can include concerns, considerations with prostae health, worsening of pre-existing sleep apnoea and fertility considerations.


One of the most discussed concerns with TRT is it’s potential impact on heart health. Studies presented mixed findings in this area until early 2024 when the large multi-centre double blinded placebo-controlled randomised study known as TRAVERSE provided compelling to say that patients on TRT are not at an increased risk of events to the general public(1). There is an excellent review article written subsequently by behemothlabzbehemothlabz.com">Testosterone Replacement Therapy (TRT) Therapy: A Review of the TRAVERSE Study", which summarises the findings of what is considered one of the largest and most robust studies on the risks and benefits of TRT(2).


At Omniya Clinic, we usethorough pre-treatment assessments to determine each patient’s cardiovascular health, ensuring TRT is safe for those with or without pre-existing heart conditions.


The relationship between testosterone therapy and prostate health has been a subject of research for decades. Historically, some doctors avoided TRT due to concerns that it could accelerate prostate cancer growth. However, according to the Endocrine Society’s clinical guidelines(3), recent data does not support a direct link between and an increased risk of prostate cancer in otherwise healthy men. Nonetheless, the guidelines recommend regular prostate monitoring for those undergoing TRT. In line with this recommendation, our team at Omniya follows a careful monitoring protocol to safeguard prostate health.


TRT can potentially worsen sleep apnea, a condition that disrupts during sleep, particularly in men who are overweight. Longterm risks of untreated sleep apnoea include heart attacks and strokes. Research published in the of Clinical Endocrinology highlights that may play a role in increasing airway resistance, which can exacerbate sleep apnoea symptoms(4). Importantly, one of the common presenting symptoms of a patient with low testosterone is difficulty losing weight and weight gain; this is also one of the commonest causes of sleep apnoea. TRT encourages weight loss and muscle gain and can be in the reversal of obstructive sleep apnoea. At Omniya, our initial assessments include a thorough examination of any pre-existing sleep disorders, helping us identify individuals at risk and adjust treatments as needed. It is if we feel someone may have sleep apnoea that this is explored and (and if required) first, before starting TRT.


For more information, please see our page on .


By supplementing testosterone, the body may reduce its own production of the hormone, which can lead to lower sperm production. This is an essential consideration for men planning to start or expand their families. To mitigate this risk, adjunctive treatments like human chorionic gonadotropin (HCG) can sometimes be used alongside TRT. Studies have found that HCG therapy could help maintain sperm production in men receiving testosterone therapy, however more research is needed in this area, particularly around the longterm use of HCG to maintain fertility(5).


Safety Measures at Omniya Clinic


Patient safety is at the heart of our program at Omniya Clinic. Here’s how we ensure that every treatment is safe, effective, and personalised:



What are the Side Effects of Testosterone Replacement Therapy (TRT)?


Just as with any medical treatment, can have side effects. However, most side effects are mild and manageable. Here are some that you may encounter:


The good news is that many of these side effects are manageable with lifestyle adjustments or to your treatment plan. At Omniya Clinic, our team is on hand to provide guidance and every step of the way.


Long-Term Considerations: What Does the Research Say?


The long-term impact of is a growing area of research. While early raised questions, more recent findings are uncovering the for long-term benefits, particularly in areas like bone health, cognitive function, and metabolic health.



Making an Informed Decision


Choosing is a highly personal decision that involves weighing the potential benefits and risks. At Omniya, we encourage all prospective patients to have open with our specialists, exploring their symptoms, goals, and any questions they may have. Here are some practical steps to consider when thinking about TRT:


We believe that knowledge is power. Our mission at Omniya Clinic is to provide every patient with the guidance they need to make informed decisions about their health and well-being.


to discuss TRT options.


The Path to Renewed Vitality Starts Here


can be a life-changing treatment for men with low testosterone. By understanding its risks, safety considerations, and side effects, you can make an empowered decision that aligns with your health goals. At Omniya Clinic London, our experienced team is to delivering safe, effective, and personalised care, helping you achieve optimal health and well-being.


If you’re experiencing symptoms of low testosterone and are considering TRT, take the first step towards renewed energy, confidence, and vitality with Omniya Clinic. Our team of experts is ready to guide you on your journey to better health.


to start your journey with TRT


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Dr Aman Chungh is a highly regarded men’s health physician and medical author whose work bridges the gap between clinical expertise and accessible health education. With over a decade of experience in general practice, he has refined an approach that seamlessly integrates insights from medicine, surgery and holistic health. His clinical journey has deepened his understanding of the interplay between hormones, mental well‐being and physical vitality - a perspective that his written contributions to the field.


A proud alumnus of the University of Southampton, Dr Chungh obtained his Bachelor of Medicine and Bachelor of Surgery degree in 2014, following his success in both a Bachelor of Science and a Bachelor of Medical Sciences. This robust foundation, combined with years of hands‐on patient care, fuels his to remaining at the forefront of medicine. As an author, he skilfully intricate medical principles into engaging, reader

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